Anastasio Bustamante, an haife shi a Jiquilpan, Michoacán a 1780. Ya yi karatun likita a Kwalejin Mining kuma yana zaune a San Luis Potosí.
Ya shiga cikin rundunar masarauta karkashin umarnin Calleja, inda ya sami mukamin Laftana. Ya bi Tsarin Iguala kuma ba da daɗewa ba ya sami amincewar Iturbide. Daga baya an zabe shi memba na Kwamitin Rikon kwarya na Gwamnati kuma Kyaftin Janar na lardunan Gabas da Yamma. A cikin 1829 ya hau kujerar mataimakin shugaban kasa bisa umarnin Guerrero, wanda ya hambarar da shi jim kadan bayan ya yi shelar Tsarin Jalapa. Ya ɗauki shugabancin zartarwa a matsayin mataimakin shugaban ƙasa daga Janairu 1830 zuwa Agusta 1832.
Bayan shekara guda an kama shi kuma jim kaɗan bayan an sake shi an tura shi zuwa Turai. A karshen yakin Texas (1836) ya isa Mexico don karbar shugabancin da ya rike har zuwa 1839. Ya zama kwamandan soja a lokacin Yakin Fasto tare da Faransa kuma ya dawo kan kujerar shugaban na wani karamin lokaci, kamar yadda ya sake an kifar da shi kuma aka tura shi Turai. Ya dawo a cikin 1844 kuma ya zama shugaban Majalisa bayan shekaru biyu. Lokacin da aka kafa zaman lafiya tsakanin Mexico da Amurka, ya karɓi umarnin sanya Guanajuato da Aguascalientes cikin tsari kuma a sasanta Sierra Gorda. Ya mutu a San Miguel Allende a 1853.
